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Sofia Hassiotis Selected Research

Infusion Pumps (Infusion Pump)

5/2016Low-dose, continuous enzyme replacement therapy ameliorates brain pathology in the neurodegenerative lysosomal disorder mucopolysaccharidosis type IIIA.

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Sofia Hassiotis Research Topics

Disease

18Mucopolysaccharidosis III (Sanfilippo Syndrome)
12/2023 - 03/2009
4Mucopolysaccharidoses
12/2023 - 01/2013
4Neurodegenerative Diseases (Neurodegenerative Disease)
12/2023 - 04/2016
4Gliosis
01/2017 - 03/2009
3Alzheimer Disease (Alzheimer's Disease)
01/2023 - 01/2018
2Amyloid Plaque
01/2023 - 01/2018
2Neuroinflammatory Diseases
01/2016 - 05/2015
1Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
12/2023
1Sandhoff Disease (Sandhoff's Disease)
06/2022
1Tay-Sachs Disease
06/2022
1Lysosomal Storage Diseases (Lysosomal Storage Disease)
06/2022
1Chronic Disease (Chronic Diseases)
10/2021
1Nervous System Diseases (Neurological Disorders)
05/2016
1Brain Diseases (Brain Disorder)
04/2016
1Infections
01/2016

Drug/Important Bio-Agent (IBA)

15N-sulfoglucosamine sulfohydrolase (sulfamidase)IBA
01/2017 - 03/2009
11EnzymesIBA
01/2017 - 07/2011
7Heparitin Sulfate (Heparan Sulfate)IBA
01/2017 - 10/2010
4Amyloid (Amyloid Fibrils)IBA
01/2023 - 01/2018
3GangliosidesIBA
12/2023 - 08/2011
3Proteins (Proteins, Gene)FDA Link
01/2023 - 03/2009
3Biomarkers (Surrogate Marker)IBA
10/2021 - 03/2015
3OligosaccharidesIBA
05/2016 - 03/2009
3GlycolipidsIBA
05/2015 - 01/2012
2CholesterolIBA
12/2023 - 08/2011
2LipidsIBA
12/2023 - 01/2016
2Filipin (Filipin III)IBA
12/2023 - 01/2016
2UbiquitinIBA
01/2017 - 03/2009
2Lysosomal Membrane ProteinsIBA
01/2017 - 01/2016
1G(M1) GangliosideIBA
12/2023
1Coloring Agents (Dyes)IBA
12/2023
1tau Proteins (tau Protein)IBA
01/2023
1Amino AcidsFDA Link
01/2023
1Dietary ProteinsIBA
01/2023
1Hexosaminidases (Hexosaminidase)IBA
06/2022
1Cholinergic Agents (Cholinergics)IBA
01/2017
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
01/2017
1Glutamic Acid (Glutamate)FDA Link
01/2017
1Choline O-Acetyltransferase (Choline Acetyltransferase)IBA
01/2017
1LectinsIBA
01/2016
1Glial Fibrillary Acidic ProteinIBA
01/2016
1G(M3) GangliosideIBA
01/2016
1Protein AggregatesIBA
06/2014
1Green Fluorescent ProteinsIBA
01/2013
1Polysaccharides (Glycans)IBA
07/2011
1mannose-6-phosphateIBA
07/2011

Therapy/Procedure

4Cannula
01/2017 - 01/2016
2Enzyme Replacement Therapy
05/2016 - 05/2015
1Spinal Infusions
01/2017
1Infusion Pumps (Infusion Pump)
05/2016
1Therapeutics
05/2016
1Injections
01/2016
1Spinal Injections
01/2015
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2013
1Stem Cell Transplantation
10/2010